Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials

Meinhard Kieser

Springer Nature Switzerland AG, 2020

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This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses.

ISBN-13
9783030495275
ISBN-10
3030495272
Publisher
Springer Nature Switzerland AG
Year
2020
Publication date
2020-11-20
Pages
396
Dimensions
162x241x32
Weight
756